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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATM
All Species:
12.42
Human Site:
T593
Identified Species:
30.37
UniProt:
Q13315
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13315
NP_000042.3
3056
350687
T593
E
G
D
L
E
N
S
T
E
V
P
P
I
L
H
Chimpanzee
Pan troglodytes
XP_001139487
3056
350692
T593
E
G
D
L
E
N
S
T
E
V
P
P
I
L
H
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q62388
3066
349469
T592
E
D
D
L
E
D
S
T
E
L
P
P
I
L
Q
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001155872
3050
347768
S591
E
E
E
M
E
E
C
S
E
L
P
P
V
L
C
Frog
Xenopus laevis
Q9DE14
2654
301441
L331
L
N
M
L
L
E
K
L
A
A
L
F
D
G
G
Zebra Danio
Brachydanio rerio
XP_002667249
1913
215524
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q5EAK6
2767
317973
L444
N
A
K
N
L
R
N
L
R
L
C
L
A
H
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001107666
3120
349933
R605
E
V
E
D
A
G
E
R
L
A
V
T
P
L
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M3G7
3856
435096
S1319
V
L
L
G
S
I
I
S
S
N
H
I
T
V
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7RZT9
2939
328678
H565
K
A
K
L
L
S
D
H
E
I
A
G
D
V
N
Conservation
Percent
Protein Identity:
100
99.4
N.A.
N.A.
N.A.
83.8
N.A.
N.A.
N.A.
69.5
20.5
35.1
N.A.
22.1
N.A.
N.A.
36.2
Protein Similarity:
100
99.7
N.A.
N.A.
N.A.
91.3
N.A.
N.A.
N.A.
82.8
39.9
46.3
N.A.
42.8
N.A.
N.A.
56.7
P-Site Identity:
100
100
N.A.
N.A.
N.A.
73.3
N.A.
N.A.
N.A.
40
6.6
0
N.A.
0
N.A.
N.A.
13.3
P-Site Similarity:
100
100
N.A.
N.A.
N.A.
86.6
N.A.
N.A.
N.A.
73.3
6.6
0
N.A.
13.3
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.9
N.A.
20.8
Protein Similarity:
N.A.
N.A.
N.A.
42.5
N.A.
40.9
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
46.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
20
0
0
10
0
0
0
10
20
10
0
10
0
0
% A
% Cys:
0
0
0
0
0
0
10
0
0
0
10
0
0
0
10
% C
% Asp:
0
10
30
10
0
10
10
0
0
0
0
0
20
0
0
% D
% Glu:
50
10
20
0
40
20
10
0
50
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% F
% Gly:
0
20
0
10
0
10
0
0
0
0
0
10
0
10
10
% G
% His:
0
0
0
0
0
0
0
10
0
0
10
0
0
10
20
% H
% Ile:
0
0
0
0
0
10
10
0
0
10
0
10
30
0
10
% I
% Lys:
10
0
20
0
0
0
10
0
0
0
0
0
0
0
10
% K
% Leu:
10
10
10
50
30
0
0
20
10
30
10
10
0
50
10
% L
% Met:
0
0
10
10
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
10
0
10
0
20
10
0
0
10
0
0
0
0
10
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
40
40
10
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% Q
% Arg:
0
0
0
0
0
10
0
10
10
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
10
10
30
20
10
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
30
0
0
0
10
10
0
0
% T
% Val:
10
10
0
0
0
0
0
0
0
20
10
0
10
20
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _